Malignant insulinoma in a child
Autor: | Rasha Deebajeh, Maher A. Sughayer, Waleed Janem, Rula Y. Goussous, Hussam Haddad, Iyad Sultan, Fatena Ajlouni |
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Rok vydání: | 2010 |
Předmět: |
Male
endocrine system Pathology medicine.medical_specialty Pediatrics endocrine system diseases business.industry Incidence (epidemiology) MEDLINE Hematology Malignant insulinoma Severe hypoglycemia Pancreatic Neoplasms medicine.anatomical_structure Oncology Pediatrics Perinatology and Child Health medicine Humans Insulinoma Pancreas business Child hormones hormone substitutes and hormone antagonists |
Zdroj: | Pediatric bloodcancer. 55(7) |
ISSN: | 1545-5017 |
Popis: | Insulinomas are rare tumors with an estimated incidence of one per 250,000 person-years. Most insulinomas are benign with less than 10% demonstrating malignant behavior, the vast majority of which occur in adults. A systemic review of the literature revealed only nine cases of malignant insulinomas occurring in children. Herein, we present a case of metastatic malignant insulinoma in a 12-year-old child. The occurrence of this diagnosis in a child, its unusual pattern of metastases and the challenging management of severe hypoglycemia make this case worth reporting. |
Databáze: | OpenAIRE |
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