The hidden world of drug interactions in anesthesia
| Autor: | Luis Alberto Tafur-Betancourt |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Drug
Intrinsic activity business.industry media_common.quotation_subject Critical Care and Intensive Care Medicine 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Pharmacokinetics 030202 anesthesiology Pharmacodynamics Anesthesia Anesthetic medicine business 030217 neurology & neurosurgery media_common Administering medications medicine.drug |
| Zdroj: | Colombian Journal of Anesthesiology. 45:216-223 |
| ISSN: | 2256-2087 |
| Popis: | Drug interactions represent the cornerstone in the basic anesthetic triangle and knowledge about such interactions contributes to a solid foundation for administering medications. This article dwells on the anesthetic drug interactions: pharmaceutical (mixing or not mixing), pharmacokinetic (alterations in distribution, metabolism, or clearance), pharmacodynamics (synergism, additive effect) and thermodynamic (affinity and intrinsic activity). The basic anesthetic triangle is a current concept and drug interactions are the cornerstone for safe anesthesia. These interactions are currently neglected and hence the anesthetist should recognize any drug interactions for a safer practice of anesthesia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|