Secretory breast carcinoma in a male child: Case report and literature review
| Autor: | Camila Girardi Fachin, Alexandre do Nascimento, Carolina Marquetto Tognolo, Elis Novochadlo Klüppel, Luiza Rodrigues da Costa, Melyssa Grignet Ribeiro |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Sentinel lymph node Malignancy Article 03 medical and health sciences 0302 clinical medicine Breast cancer Case report Biopsy medicine Adjuvant therapy Excision margins skin and connective tissue diseases Mastectomy medicine.diagnostic_test business.industry medicine.disease 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Radiology Breast neoplasms Breast carcinoma business Secretory Breast Carcinoma |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| DOI: | 10.1016/j.ijscr.2020.07.040 |
| Popis: | Highlights • Even slow growing mammary lesions in a male child may be malignant. • Secretory breast cancer positive for estrogen and progesterone receptors is very rare in a male child. • Secretory breast cancer after surgical excision usually does not require adjuvant therapy. Introduction The secretory breast carcinoma is very rare in children. It represents less than 1% of malignancy cases in childhood and is even less common in males, with 15 cases reported until 2004. Therefore, the aim of this study is to report a male child with breast carcinoma and review literature. Presentation of case A 14-year-old male patient with a history of a painless slow-growing lump in the left breast and, five years later, onset of yellow discharge from the papilla. Ultrasound scanning demonstrated a well- defined, regular, homogeneous and hypoechoic mass. Nodule excision was initially performed, followed by mastectomy, due to compromised radial margin. Immunohistochemistry revealed weakly positive estrogen and progesterone receptors. Adjuvant therapy was not required. Sixteen months after resection, the patient is well with no complaints or recurrence. Discussion Due to its rarity, there is no therapeutic guideline. Although the recommended treatment is still surgical excision, there is no consensus as to its extent. Prognosis is usually favorable. Our patient was submitted to mastectomy with sentinel lymph node biopsy due to compromised radial margin. Conclusion Secretory breast carcinoma is a rare form of breast cancer, especially in male children; which hampers standardization of diagnosis, treatment and prognosis establishment. |
| Databáze: | OpenAIRE |
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