Additional file 3 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter

Autor: Miedema, Anneke, Gerrits, Emma, Brouwer, Nieske, Jiang, Qiong, Kracht, Laura, Meijer, Michel, Nutma, Erik, Peferoen-Baert, Regina, Pijnacker, Anna T. E., Wesseling, Evelyn M., Wijering, Marion H. C., Gabius, Hans-Joachim, Amor, Sandra, Eggen, Bart J. L., Kooistra, Susanne M.
Rok vydání: 2022
DOI: 10.6084/m9.figshare.19090713.v1
Popis: Additional file 3: Figure S3. Supplementary data related to figure 3. (a) Volcano plot depicting significantly differentially expressed genes between Hs8 and Hs6 samples. (b) Bar plots depicting top 20 gene ontology terms associated with DEGs between Hs8 and Hs6 cells. (c) Heatmap depicting expression weighted gene set enrichment scores of microglia subcluster markers derived from Gerrits et al. (2021) in the human MS dataset. Asterisks depict significant enrichments (p < 0.05). Abbreviations: NACT = normal appearing cortical tissue; NAWM = normal appearing white matter; WML = white matter lesion.
Databáze: OpenAIRE