Protective effects of organic solvent fractions from the seeds of Vigna radiata L. wilczek against antioxidant mechanisms
Autor: | Ill-Min Chung, Hyung-In Moon, Sun-Jin Kim, Min-A Yeo |
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Rok vydání: | 2010 |
Předmět: |
Antioxidant
Free Radicals Health Toxicology and Mutagenesis medicine.medical_treatment Radiata Trolox equivalent antioxidant capacity Chemical Fractionation Toxicology Vigna chemistry.chemical_compound medicine Phenol Humans Food science Lipoprotein oxidation Reactive nitrogen species chemistry.chemical_classification Reactive oxygen species biology Ethanol Chemistry Plant Extracts food and beverages Fabaceae General Medicine Free Radical Scavengers biology.organism_classification Lipoproteins LDL Biochemistry Seeds Solvents Oxidation-Reduction |
Zdroj: | Humanexperimental toxicology. 30(8) |
ISSN: | 1477-0903 |
Popis: | This study was conducted to evaluate the in vitro scavenging activity and inhibitory effect of low-density lipoprotein oxidation of pro-oxidant reactive species in response to treatment with organic solvent fractions from mung bean (seeds of Vigna radiata) extracts using various screening methods including biological and non-biological oxidants. The antioxidant activity of different organic solvent fractions from mung bean extracts were studied in vitro methods by evaluating the total phenol components, measuring the antioxidant activity by trolox equivalent antioxidant capacity, measuring the scavenging effects on reactive oxygen species and on reactive nitrogen species as well as measuring the inhibitory effect on Cu2+-induced human low-density lipoprotein oxidation. The mung bean extracts were found to have a potent scavenging activity against all of the reactive species tested as well as an inhibitory effect on low-density lipoprotein oxidation, the studied mung bean was revealed to be very effective against the evaluated pro-oxidant species, including reactive oxygen species and on reactive nitrogen species. |
Databáze: | OpenAIRE |
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