Rescue of Interferon Induced Bone Marrow Aplasia in a Patient with Chronic Myeloid Leukemia by Allogeneic Bone Marrow Transplant
| Autor: | Jeffrey H. Lipton, H Solow, J Rifkind, A Alabdulaaly, Hans A. Messner |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Cancer Research Alpha interferon Bone Marrow Aplasia Philadelphia chromosome Myelogenous Bone Marrow Leukemia Myelogenous Chronic BCR-ABL Positive hemic and lymphatic diseases Cyclosporin a Humans Transplantation Homologous Medicine Bone Marrow Diseases Bone Marrow Transplantation business.industry Interferon-alpha Myeloid leukemia Hematology medicine.disease Transplantation Leukemia Oncology Immunology Female business |
| Zdroj: | Leukemia & Lymphoma. 45:175-177 |
| ISSN: | 1029-2403 1042-8194 |
| DOI: | 10.1080/1042819031000139774 |
| Popis: | A patient with chronic phase Philadelphia chromosome positive CML, developed severe protracted bone marrow hypoplasia after interferon therapy. This complication did not respond to two courses of immunosuppressive therapy with anti-thymocyte globulin, cyclosporin A and prednisone. The patient continued to be transfusion dependent with persistence of Philadelphia chromosome. Allogeneic BMT restored normal hematopoeisis. |
| Databáze: | OpenAIRE |
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