Immunization of chickens with live Newcastle disease vaccine adjuvanted with oil

Autor: Itzchak Samina, J. Brenner, Ben-Ami Peleg
Rok vydání: 1993
Předmět:
Zdroj: Vaccine. 11:1074-1076
ISSN: 0264-410X
Popis: Chickens of various ages and breeds were vaccinated subcutaneously with Newcastle disease live-in-oil vaccines. These vaccines were prepared immediately prior to the vaccination by mixing the lyophilized live vaccine with the oil adjuvant, which was kept at room temperature. The live-in-oil vaccines were shown to be 30-50 times more effective in efficacy tests than either the same vaccines reconstituted in water or killed-in-oil vaccines. In addition to its biological advantage, the method of preparation of live-in-oil vaccine saves the expensive space of cold storage and shipment necessary for conventional killed-in-oil vaccines.
Databáze: OpenAIRE