HSV-2 meningoencephalitis in an immunocompetent young man: what is the pathogenesis and what is the treatment?
| Autor: | M. P. Fernandez-Gerlinger, Flore Rozenberg, J. Grenet, A. Meffre, S. Au, M. Bojanova, E. Rouveix, S. Greffe |
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| Rok vydání: | 2015 |
| Předmět: |
Sexually transmitted disease
Adult Male viruses Herpesvirus 2 Human Acyclovir medicine.disease_cause Antibodies Viral Antiviral Agents Polymerase Chain Reaction Pathogenesis Meningoencephalitis Virology medicine Humans Aciclovir Herpes Genitalis business.industry Brain Herpes Simplex medicine.disease Radiography Infectious Diseases Herpes simplex virus Immunology Encephalitis Herpes Simplex Immunocompetence business Encephalitis medicine.drug |
| Zdroj: | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 69 |
| ISSN: | 1873-5967 |
| Popis: | Herpes simplex encephalitis is rarely caused by herpes simplex virus type 2 (HSV-2) after the neonatal period. The pathogenesis of HSV-2 encephalitis is not known and its treatment has not been discussed. We report a case of mild meningoencephalitis secondary to HSV-2 primary infection after sexual risk behaviour in a healthy young man. The diagnosis was established upon clinical, biological and electroencephalographic criteria. Aciclovir treatment led to rapid clinical improvement. This case highlights HSV-2 as a rare cause of meningoencephalitis, and questions the management of this rare manifestation of HSV-2 infection. |
| Databáze: | OpenAIRE |
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