Routine use of daily oral vitamin K to treat infants with cystic fibrosis
| Autor: | Sophie T. Cottam, Gary Connett |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Vitamin Male medicine.medical_specialty Vitamin K Cystic Fibrosis Administration Oral Late onset Breast milk Gastroenterology Cystic fibrosis chemistry.chemical_compound Internal medicine Vitamin K deficiency medicine Coagulopathy Humans business.industry Infant Newborn Infant Vitamins Haemorrhagic disease of the newborn medicine.disease Surgery chemistry Pediatrics Perinatology and Child Health Oral vitamin Vitamin K Deficiency business Tomography X-Ray Computed Intracranial Hemorrhages |
| Zdroj: | Paediatric respiratory reviews. 16 |
| ISSN: | 1526-0550 |
| Popis: | Vitamin K is routinely administered after birth in the UK to prevent haemorrhagic disease of the newborn. Despite this, vitamin K-deficient coagulopathy still occurs in infants with high morbidity and mortality. Up to 50% of late onset bleeding presents with intracranial haemorrhage. The risk of developing vitamin K coagulopathy is higher in infants with cystic fibrosis (CF) and those that are exclusively breast fed due to low vitamin K levels in breast milk and intestinal changes in bacterial flora. Oral vitamin K supplementation is a simple addition to routine CF treatment during infancy to prevent complications from significant coagulopathy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect