Modified Antiretroviral Treatment Access Study (MARTAS): A Randomized Controlled Trial of the Efficacy of a Linkage‐to‐Care Intervention Among HIV-Positive Patients in Ukraine
| Autor: | Oleksandr Neduzhko, Tetiana Kiriazova, Yuliia Sereda, Oleksandr Postnov, Roksolana Kulchynska, Janet J. Myers, Trista Bingham, Timothy P. Flanigan |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Social Psychology Human immunodeficiency virus (HIV) HIV Infections medicine.disease_cause Article law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Pregnancy law Patient-Centered Care Intervention (counseling) Internal medicine Retention in Care Antiretroviral treatment Humans Medicine 030212 general & internal medicine Aged Linkage (software) 030505 public health business.industry Public health Public Health Environmental and Occupational Health Standard of Care Middle Aged Patient Acceptance of Health Care medicine.disease Health psychology Treatment Outcome Infectious Diseases Anti-Retroviral Agents Female Ukraine 0305 other medical science business Case Management |
| Zdroj: | AIDS Behav |
| ISSN: | 1573-3254 1090-7165 |
| Popis: | Between October 2015 and March 2018, we conducted the Modified Antiretroviral Treatment Access Study (MARTAS), a nurse-delivered case management intervention to improve linkage-to-care for persons recently tested HIV positive. Adult participants from nine urban clinics in three regions of Ukraine were randomized to either MARTAS or standard of care (SOC) using individual, parallel, two-arm design. The main study outcome was linkage-to-care (defined as registration at an HIV clinic) within a 3-month period from enrollment in the study. Intention-to-treat analysis of MARTAS (n = 135) versus SOC (n = 139) showed intervention efficacy in linkage to HIV care (84.4% vs. 33.8%; adjusted RR 2.45; 95% CI 1.72, 3.47; p < 0.001). MARTAS is recommended for implementation in Ukraine and may be helpful in other countries with similar gaps in linkage-to-care. Clinicaltrials.gov registration number: NCT02338024. |
| Databáze: | OpenAIRE |
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