Central Hyperthyroidism due to Thyroid-Stimulating Hormone-Secreting Pituitary Microadenoma in an Adolescent Boy: Case Report and Review of the Literature
| Autor: | Thieu-Thi Tra My, Le Hoang Bao, Tran Viet Thang, Phan Cong Chien, Nguyen Minh Duc, Tran Quang Nam |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Primary Hyperthyroidism
Pituitary gland medicine.medical_specialty endocrine system endocrine system diseases Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Case Report Gastroenterology Diseases of the endocrine glands. Clinical endocrinology 03 medical and health sciences 0302 clinical medicine Thyroid-stimulating hormone Pituitary adenoma 030225 pediatrics Internal medicine medicine medicine.diagnostic_test business.industry Pituitary tumors Magnetic resonance imaging RC648-665 medicine.disease medicine.anatomical_structure Somatostatin business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Case Reports in Endocrinology Case Reports in Endocrinology, Vol 2021 (2021) |
| ISSN: | 2090-651X 2090-6501 |
| Popis: | Thyroid-stimulating hormone- (TSH-) secreting pituitary adenoma (TSH-oma) is a rare cause of secondary hyperthyroidism and can be misdiagnosed as primary hyperthyroidism. We report a case of a 15-year-old male patient who was one of two monozygotic twins and exhibited hyperthyroidism syndrome. The laboratory results showed secondary hyperthyroidism, with increased levels of free T3 (FT3) and free T4 (FT4) and no TSH inhibition. Magnetic resonance imaging (MRI) and histopathological examination of the pituitary gland confirmed pituitary microadenoma. The patient was treated with methimazole, propranolol, and somatostatin analogs to restore euthyroidism before undergoing an endoscopic transsphenoidal resection of the pituitary tumor. After surgery, the hyperthyroidism symptoms improved, thyroid hormones normalized, and MRI of the pituitary gland showed the complete removal of the tumor with no recurrence after 2 years of follow-up. |
| Databáze: | OpenAIRE |
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