Expert Learning System Network for Diagnosis of Breast Calcifications
Autor: | Eric I. Gruenstein, Myron Moskowitz, Edward A. Patrick, Vineet T. Mansukhani |
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Rok vydání: | 1991 |
Předmět: |
medicine.medical_specialty
Pathology Test group education Expert Systems Image processing Breast Diseases Breast cancer Biopsy medicine Humans Radiology Nuclear Medicine and imaging Statistical analysis medicine.diagnostic_test Breast calcification business.industry Calcinosis General Medicine medicine.disease Test case Radiographic Image Interpretation Computer-Assisted Female Radiology business Software Mammography |
Zdroj: | Investigative Radiology. 26:534-539 |
ISSN: | 0020-9996 |
Popis: | Breast calcification diagnosis was studied by using clinical findings and computerized image processing of a mammogram in a network of trained expert learning systems (Outcome Advisor [OA]). The system was tested with records not used for training and performance was compared with radiologist. The network was 72% accurate in classifying clusters of calcifications as malignant or benign over a set of test cases radiologists had considered "hard-to-diagnose calcifications," and referred for biopsy. The radiologists had decided to conduct biopsy by selecting an equal number of positive and negative cases for the test group; thus the radiologists' performance with respect to categories of benign versus malignant was constrained to be 50/50. Statistical analysis shows only a 2% probability that the observed accuracy of 72% was a chance performance in recognizing whether a cluster is benign or malignant. The feasibility of developing a network of OAs for diagnosing breast cancer integrating digital image processing of mammograms is promising. |
Databáze: | OpenAIRE |
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