A two-step strategy for delivering particles to targets hidden within microfabricated porous media
| Autor: | Huanshu Tan, Todd M. Squires, Amr I. Abdel-Fattah, Anirudha Banerjee, Nan Shi, Xiaoyu Tang |
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| Rok vydání: | 2021 |
| Předmět: |
endocrine system
Multidisciplinary Computer science Distributed computing Two step digestive oral and skin physiology technology industry and agriculture Design elements and principles SciAdv r-articles complex mixtures Engineering Low permeability Small particles Porous medium Research Articles Research Article Applied Physics |
| Zdroj: | Science advances, vol 7, iss 33 Science Advances |
| Popis: | Our strategy delivers colloidal objects to targets within porous media without needing to know the location of the targets. The delivery of small particles into porous environments remains highly challenging because of the low permeability to the fluids that carry these colloids. Even more challenging is that the specific location of targets in the porous environment usually is not known and cannot be determined from the outside. Here, we demonstrate a two-step strategy to deliver suspended colloids to targets that are “hidden” within closed porous media. The first step serves to automatically convert any hidden targets into soluto-inertial “beacons,” capable of sustaining long-lived solute outfluxes. The second step introduces the deliverable objects, which are designed to autonomously migrate against the solute fluxes emitted by the targets, thereby following chemical trails that lead to the target. Experimental and theoretical demonstrations of the strategy lay out the design elements required for the solute and the deliverable objects, suggesting routes to delivering colloidal objects to hidden targets in various environments and technologies. |
| Databáze: | OpenAIRE |
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