The synthesis of a water soluble complement activating polyacrylic acid-IgG polymer

Autor:	Gottfried Schmer, Wolfgang Müller, Ruth Henderson
Rok vydání:	1994
Předmět:	Materials science Polymers Complement Pathway Alternative Biomedical Engineering Biophysics Acrylic Resins chemical and pharmacologic phenomena Bioengineering Complement C5a Biomaterials chemistry.chemical_compound Complement C4b Complement Pathway Classical Complement Activation chemistry.chemical_classification Complement C1q Polyacrylic acid Water Complement C4 Polymer biochemical phenomena metabolism and nutrition Immune complex Peptide Fragments Complement (complexity) Complement system Water soluble chemistry Biochemistry Solubility Immunoglobulin G Complement C3b Alternative complement pathway Complement C3a
Zdroj:	Journal of biomaterials science. Polymer edition. 6(1)
ISSN:	0920-5063
Popis:	Polyacrylic acid-IgG polymer (PAA-IgG) activates the classical and alternative pathway of complement as shown by specific Clq-(IgG-PAA) interaction and the generation of C4d, Bb, C3b, C3a and C5a. This water soluble and stable PAA-IgG polymer represents a model substance for the study of humoral and cellular inflammatory mechanisms, mediated by the complement system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1a0f0aacee4bb96229487b9831a71a https://pubmed.ncbi.nlm.nih.gov/7947474 Zobrazit plný text záznamu