A skincare containing retinol adenosine and hyaluronic acid optimises the benefits from a type A botulinum toxin injection

Autor:	Benjamin Ascher, Anne Bouloc, Leila Kanoun-Copy, Florence Benech, Chantal Fanchon
Rok vydání:	2012
Předmět:	Adult medicine.medical_specialty Adenosine Botulinum toxin injection Dermatology Pharmacology Administration Cutaneous law.invention chemistry.chemical_compound Imaging Three-Dimensional Double-Blind Method Randomized controlled trial law Hyaluronic acid medicine Humans Botulinum Toxins Type A Hyaluronic Acid Vitamin A business.industry Retinol Middle Aged Glabella Surgery Regimen medicine.anatomical_structure chemistry 3d image Face Drug Therapy Combination Female business medicine.drug
Zdroj:	Journal of Cosmetic and Laser Therapy. 14:234-238
ISSN:	1476-4180 1476-4172
DOI:	10.3109/14764172.2012.712700
Popis:	A monocentre double-blind two parallel group clinical study was conducted to assess whether a new skincare regimen containing retinol, adenosine and hyaluronic acid, applied after the injection of botulinum toxin A to the glabellar area, provided a beneficial effect.Standardised photographs acquired using LifeViz cameras and zoomed pictures of the glabella and of the crow's feet areas were analysed with automatic well-defined procedures. Perceived efficacy and tolerance were also analysed by comparison between the two groups.A beneficial effect versus placebo-treated group was proven in the group having topically applied the new skincare regimen for 2 months following botulinum toxin A injection with no touch up after 1 month. 3D image analysis showed more rapid results on D10 and enhanced efficacy on M2. Moreover, a beneficial effect independent of injection was measured in the crow's feet area, and analysis of the self-evaluation questionnaire showed enhanced efficacy perceived by the volunteers.A specially developed skincare regimen applied immediately after botulinum toxin A injection completes the beneficial effect of the injection on the glabellar area and offers clinical benefits in fine lines, wrinkles and smoothness on the whole face.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0d76be8018051dab147fe509ffb44e https://doi.org/10.3109/14764172.2012.712700 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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