The first epidemic of dengue hemorrhagic fever in the People's Republic of China
| Autor: | Wen-Zhou Chen, Qiu-Qian Chen, Fu-Xi Qiu, Qi-Ya Ho, Bi-Wei Zhao, Zhi-Guo Zhao |
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| Rok vydání: | 1991 |
| Předmět: |
Serotype
Adult Male medicine.medical_specialty China Mosquito Control Adolescent Aedes aegypti Dengue fever Disease Outbreaks Dengue Aedes Virology Internal medicine Case fatality rate Medicine Animals Humans Child biology business.industry Dengue Virus Middle Aged medicine.disease biology.organism_classification Insect Vectors Pneumonia Mosquito control Infectious Diseases 2009 Bolivian dengue fever epidemic Child Preschool Parasitology Female Viral disease business Gastrointestinal Hemorrhage |
| Zdroj: | The American journal of tropical medicine and hygiene. 44(4) |
| ISSN: | 0002-9637 |
| Popis: | The first epidemic of dengue in China associated with significant severe and fatal hemorrhagic disease which met the World Health Organization case definition occurred on Hainan Island in 1985-1986. The epidemic began in Zhan County in September 1985, spread throughout the coastal areas, and ultimately involved 13 counties and cities of the island in 1986. The mosquito vector was Aedes aegypti. The morbidity associated with dengue infection on Hainan Island was 1,913 per 100,000 residents, with a case fatality rate of 0.25%. Severe disease was more prevalent in the 10-29-year-old age group. Principal clinical features in laboratory-confirmed cases were fever, osteoarthralgia, hemorrhage and/or shock, and thrombocytopenia. Complications such as acute intravascular hemolysis, diffuse intravascular coagulation, hemoconcentration, pleural effusion, altered mentality, and pneumonia were also observed. One hundred twenty-five isolates of dengue 2 virus were recovered from acute-phase serum samples from 278 patients, and 5 strains of this same virus serotype were isolated from 5 pools of adult Ae. aegypti. |
| Databáze: | OpenAIRE |
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