Vaccine-Preventable Diseases Requiring Hospitalization
| Autor: | Parvathi Kumar, Barbara E. Ostrov, Bilaal Ahmed, Gregory Williamson, Jessica E. Ericson |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Communicable Diseases 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans 030212 general & internal medicine Child Chickenpox Immunization Programs Tetanus business.industry Vaccination Infant medicine.disease Confidence interval Hospitalization Pneumococcal infections Immunization Child Preschool Relative risk Pediatrics Perinatology and Child Health Female Vaccine-preventable diseases Amish business |
| Zdroj: | Pediatrics. 140 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2017-0298 |
| Popis: | BACKGROUND: Plain children often have lower immunization rates than non-Plain children. Penn State Health Children’s Hospital is a tertiary medical center with large nearby Plain (Amish and Mennonite) communities. We sought to describe the characteristics of children hospitalized with vaccine-preventable diseases (VPDs). We hypothesized that Amish children would have a higher risk of VPDs than non-Amish children. METHODS: International Classification of Diseases, Ninth Revision codes were used to identify patients RESULTS: There were 215 children with 221 VPDs. Most occurred in non-Plain children: 179 of 221 (81%). Except for pneumococcal infections, VPD occurred mostly in unvaccinated or immunocompromised children, regardless of Plain affiliation. There were 15 Haemophilus influenzae type b and 5 tetanus infections that occurred in children with an unvaccinated or unknown vaccination status. The risk of a VPD requiring hospitalization was greater for Amish than for non-Plain children (risk ratio: 2.67 [95% confidence interval: 1.87–3.82]). There was a strong correlation between Plain affiliation and lack of vaccination (r = −0.63, P < .01). CONCLUSIONS: Amish children had an increased risk of a VPD requiring hospitalization than non-Plain children. With the exception of those with pneumococcal disease, most vaccinated children hospitalized with a VPD were immunocompromised. |
| Databáze: | OpenAIRE |
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