Intraoperative consultation of central nervous system lesions. Frozen section, cytology or both?
| Autor: | Amirnader Emami Razavi, Hayedeh Haeri, Neda Zargari, Nargess Shahbazi, Mehdi Zeinalizadeh, Farid Azmoudeh-Ardalan, Ali Haidari Sharifabadi, Malahat Tahvildari |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Intra operative Pathology Surgical Biopsy Cytodiagnosis Intraoperative consultation Central nervous system Diagnostic accuracy Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Central Nervous System Diseases Cytology medicine Frozen Sections Humans 030212 general & internal medicine Referral and Consultation Frozen section procedure Intraoperative Care medicine.diagnostic_test business.industry Reproducibility of Results Cell Biology Middle Aged Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis Surgical biopsy Female Radiology business |
| Zdroj: | Pathology - Research and Practice. 212:179-184 |
| ISSN: | 0344-0338 |
| DOI: | 10.1016/j.prp.2015.08.009 |
| Popis: | Objective Frozen section is the traditional method of assessing central nervous system (CNS) lesions intraoperatively. Our aim is to determine the diagnostic accuracy of frozen section and/or cytological evaluation of CNS lesions in our center. Study design A total of 157 patients with CNS lesions underwent open surgical biopsy or excision in our center during a period of 2 years (2012–2013). All specimens were studied cytologically; of these specimens, 146 cases were also examined by frozen section. Cytology and frozen section slides were studied separately by two general pathologists who were blind to final diagnoses. The final diagnoses were based on permanent sections and IHC studies. Results The accuracy rates of frozen section analysis and cytological evaluation were 87% and 86%, respectively. If the two methods were considered together, the accuracy rate improved to about 95%. Conclusions Cytological evaluation is an acceptable alternative to frozen section analysis and also a great supplement to the diagnosis of CNS lesions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect