Restless leg syndrome in children with celiac disease
| Autor: | Halil Kocamaz, Hüseyin Per, Sedat Isikay, Kursat Bora Carman, Nurgül Işıkay |
|---|---|
| Přispěvatelé: | HKÜ, Sağlık Bilimleri Fakültesi, Fizyoterapi ve Rehabilitasyon Bölümü |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Cross-sectional study correlation analysis Gastroenterology 0302 clinical medicine iron patient acuity Surveys and Questionnaires Celiac disease 030212 general & internal medicine Restless legs syndrome Restless leg syndrome Age of Onset cyanocobalamin Child Children medicine.diagnostic_test adult vitamin Complete blood count Anemia Vitamins female disease severity Adolescent Blood Cell Count Case-Control Studies Celiac Disease/blood/*complications Female Ferritins/blood Humans Patient Acuity Prevalence Restless Legs Syndrome/*etiology Vitamins/blood onset age medicine.medical_specialty prevalence complication Article 03 medical and health sciences folic acid blood Internal medicine Restless Legs Syndrome mental disorders medicine Vitamin D and neurology cross-sectional study controlled study Vitamin B12 human business.industry questionnaire ferritin disease association Case-control study hemoglobin case control study medicine.disease major clinical study 25 hydroxyvitamin D Pediatrics Perinatology and Child Health Ferritins Age of onset business 030217 neurology & neurosurgery |
| Popis: | Işıkay S, Işıkay N, Per H, Çarman KB, Kocamaz H. Restless leg syndrome in children with celiac disease. Turk J Pediatr 2018; 60: 70-75. Celiac disease (CD) is an immune-mediated enteropathy triggered by ingestion of dietary gluten in genetically predisposed individuals. The aim of the study was to determine the prevalence of restless leg syndrome (RLS) in children with CD and to investigate the associated factors for RLS. Totally 494 children with the ages ranging between 11-18 years were included. Among those, 226 were under follow-up with CD and constituted the study group while other 268 children did not have any symptoms or signs associated with CD and established the control group. The demographic data, educational status and routine laboratory data of children including complete blood count, ferritin, vitamin B12, foliate and 25 (OH) vitamin D levels were recorded. The RLS prevalence and associated symptoms of children were defined with a questionnaire. There was no statistically significant difference between the 2 groups regarding the age and gender. Moreover, RLS prevalence was also similar in both groups (3.5% vs 3.0% in CD and control groups, respectively, p=0.98). However, interestingly, in CD group, the mean age of the patients at the onset of RLS symptoms was statistically significantly younger (p=0.02) and the disease was more severe (p=0.026) than the control group. In correlation analysis in CD group, the RLS severity significantly negatively correlated with serum ferritin, folic acid or 25 (OH) vitamin D levels in Celiac disease group. In this study we did not determine an increased prevalence of RLS in children with CD. However, in CD group, the age at the onset of RLS symptoms was significantly younger and the disease was more severe in CD group compared with the control cases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|