Respiratory Syncytial Virus-Associated Hospitalizations in Children With Neurological Disorders, 2006–2015

Autor:	Gayle E Langley, Fiona Havers, Georgina Peacock, Rebecca M. Dahl, Erica Billig Rose
Rok vydání:	2021
Předmět:	Pediatrics medicine.medical_specialty Population Psychological intervention Respiratory Syncytial Virus Infections Virus Hospitalization rate 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans 030212 general & internal medicine Respiratory system Child education education.field_of_study Medicaid business.industry Infant General Medicine Confidence interval Hospitalization Infectious Diseases Respiratory Syncytial Virus Human Pediatrics Perinatology and Child Health Nervous System Diseases business Pediatric population
Zdroj:	Journal of the Pediatric Infectious Diseases Society. 10:951-957
ISSN:	2048-7207
DOI:	10.1093/jpids/piab017
Popis:	Background We quantified the risk of respiratory syncytial virus (RSV) hospitalizations and severe outcomes among children with neurological disorders. Methods We estimated RSV-specific and RSV-associated hospitalization rates using International Classification of Diseases, Ninth Revision (ICD-9) codes from 2 insurance claims IBM MarketScan Research Databases (Commercial and Multi-State Medicaid) from July 2006 through June 2015. For comparison, a simple random sample of 10% of all eligible children was selected to represent the general population. Relative rates (RRs) of RSV hospitalization were calculated by dividing rates for children with neurological disorders by rates for children in the general population by age group and season. Results The RSV-specific hospitalization rate for children with any neurological condition was 4.2 (95% confidence interval [CI]: 4.1, 4.4) per 1000 person-years, and the RSV-associated hospitalization rate was 7.0 (95% CI: 6.9, 7.2) per 1000 person-years among children Conclusions Our population-based study of children with neurological disorders found that the risk of RSV hospitalization was 6 to 12 times higher among children with neurological disorders than among the general pediatric population. These findings should be considered when determining who should be targeted for current and future RSV interventions.
Databáze:	OpenAIRE
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