Paclitaxel coated-stent for early-onset thrombosis after liver transplantation

Autor: Daniel Zamora-Valdés, María Saraí González-Huezo, José L. Victoria-Campos, María V. Zea-Medina, Ricardo Mondragón-Sánchez, Jesús Reyes-Corona
Rok vydání: 2007
Předmět:
Zdroj: Annals of Hepatology, Vol 6, Iss 4, Pp 272-275 (2007)
ISSN: 1665-2681
DOI: 10.1016/s1665-2681(19)31911-8
Popis: Hepatic artery thrombosis (HAT) is the most common vascular complication of orthotopic liver transplantation (OLT) and constitutes a potential emergency during the postoperative period. Surgical revascularization and retransplantation are the treatments of choice for this condition. The aim of this report is to present long-term follow-up on survival and graft function of three patients with paclitaxel-coated hepatic artery stents placed percutaneously after early-onset HAT. Three patients developed early onset HAT after cadaveric-donor OLT in a tertiary care center in Mexico. These patients were treated percutaneously with balloon angioplasty and paclitaxel-coated stents. After 24 months or more of follow-up, 2 patients present total occlusion of the stent and one patient, intra-stent stenosis; interestingly, all patients have normal graft function and excellent quality of life. In conclusion, although balloon angioplasty and stent placement may be a therapeutic option for suitable patients with early-onset HAT after OLT, long-term patency is unlikely even with the use of paclitax-el-coated materials.
Databáze: OpenAIRE