Antibody response to plague vaccination in humans as assayed by staphylococcal radioimmune precipitation (St-RIP) test
| Autor: | James E. Williams, Frederick L. Schaffer, M. E. Soergel |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Staphylococcus aureus
Hemagglutination Yersinia pestis Immunization Secondary Radioimmunoassay Bubonic plague General Biochemistry Genetics and Molecular Biology Immunity medicine Humans Staphylococcal Protein A Immunoassay Plague Vaccine biology business.industry Hemagglutination Tests medicine.disease Antibodies Bacterial Precipitin Tests Virology Vaccination Immunization Immunology biology.protein Plague vaccine Antibody business |
| Zdroj: | Journal of Biological Standardization. 9:265-276 |
| ISSN: | 0092-1157 |
| DOI: | 10.1016/s0092-1157(81)80051-0 |
| Popis: | The staphylococcal radioimmune precipitation (St-RIP) test was applied to sera of laboratory personnel who had been vaccinated against plague. Antibodies were detected in the majority of 117 sera from 55 human vaccine recipients; a few individuals appeared to be immunologically nonresponsive since they failed to produce detectable antibodies. Highly significant statistical correlations were observed among St-RIP, indirect hemagglutination, and mouse protection index tests. Increases in antibody level were usually observed upon primary and booster vaccination. |
| Databáze: | OpenAIRE |
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