Traditionally Used Sideritis cypria Post.: Phytochemistry, Nutritional Content, Bioactive Compounds of Cultivated Populations
| Autor: | Nikolaos Tzortzakis, Helen Skaltsa, Chryssoula Drouza, Ekaterina-Michaela Tomou, Antonios Chrysargyris, Krystalia Lytra |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Infusions Leaves Melittoside Phytochemistry Iridoid medicine.drug_class Cultivation Agricultural Biotechnology leonoside A Population melittoside Flowers Lamalboside Flavones Leonoside A 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Chlorogenic acid lamalboside medicine Pharmacology (medical) education Original Research Pharmacology chemistry.chemical_classification education.field_of_study flowers biology Traditional medicine Agricultural Sciences lcsh:RM1-950 Phenylethanoid biology.organism_classification infusions Sideritis cypria lcsh:Therapeutics. Pharmacology 030104 developmental biology cultivation chemistry 030220 oncology & carcinogenesis Sideritis leaves |
| Zdroj: | Frontiers in Pharmacology Frontiers in Pharmacology, Vol 11 (2020) |
| ISSN: | 1663-9812 |
| Popis: | The authors are grateful to the Cyprus University of Technology Open Access Author Fund. Sideritis species are recognized as important medicinal plants and their commercial demand is continuously on the rise both in the European and in the global market. Consequently, the cultivation of Sideritis species has been occurred to successfully meet the need for mass production of high-quality plant material. The present study was undertaken in order to investigate the chemical composition of cultivated S. cypria. Infusions of flowers and leaves were prepared separately, according to the European Medicine Agency (EMA) monograph. The infusion of the flowers revealed the presence of four flavones, isoscutellarein-7-O-[6'″-O-acetyl-β-D-allopyranosyl-(1→2)-β-D-glucopyranoside, its 4'-O-methyl-derivative, 4'-O-methyl-hypolaetin-7-O-[6'″-O-acetyl-β-D-allopyranosyl-(1→2)-β-D-glucopyranoside, and isoscutellarein-7-O-[6'″-O-acetyl-β-D-allopyranosyl-(1→2)]-6″-O-acetyl-β-D-glucopyranoside; four phenylethanoid glucosides, acteoside, leucosceptoside A, lamalboside, and leonoside A; one iridoid, melittoside, and one phenolic acid, chlorogenic acid, while the infusion of the leaves of the same population afforded the same first two flavones; five phenylethanoid glucosides, acteoside, leucosceptoside A, lavandulifolioside, leonoside A, and lamalboside; melittoside and chlorogenic acid. The structural elucidation of the isolated compounds was undertaken by high-field NMR spectroscopy. Moreover, the essential oils of the flowers and leaves were studied by GC-MS, separately. In addition, the mineral, bioactive compounds, protein and carbohydrate contents were evaluated for both plant materials. |
| Databáze: | OpenAIRE |
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