Nanosponges: A Novel Class of Drug Delivery System - Review
| Autor: | S. Selvamuthukumar, Manavalan Rajappan, Singireddy Anandam, Kannan Krishnamoorthy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Drug
Computer science media_common.quotation_subject Pharmaceutical Science lcsh:RS1-441 Nanotechnology lcsh:Pharmacy and materia medica Drug Delivery Systems Complex chemistry Nanosponges Aqueous solubility Animals Humans Particle Size media_common Pharmacology Class (computer programming) Drug Carriers lcsh:RM1-950 Nanostructures lcsh:Therapeutics. Pharmacology Targeted drug delivery Target site Pharmaceutical Preparations Solubility Drug delivery |
| Zdroj: | Journal of Pharmacy & Pharmaceutical Sciences, Vol 15, Iss 1 (2012) Scopus-Elsevier |
| ISSN: | 1482-1826 |
| Popis: | Effective targeted drug delivery systems have been a dream for a long time, but it has been largely frustrated by the complex chemistry that is involved in the development of new systems. The invention of nanosponges has become a significant step toward overcoming these problems. Nanosponges are tiny sponges with a size of about a virus, which can be filled with a wide variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page. |
| Databáze: | OpenAIRE |
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