Effect of parenteral nutrition in oxygen escalation/de-escalation in SARS-CoV-2 infected patients who are pre-intubation: A multicenter, observational study
Autor: | Farbod Raiszadeh, Gary Brandeis, Robert T. Faillace, Kritika Subramanian, Nadia Solomon, Vidya Menon |
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Rok vydání: | 2021 |
Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medicine.medical_treatment Oxygen requirements Malaise Internal medicine Intubation Intratracheal Humans Pre-intubation Medicine Intubation Retrospective Studies Nutrition and Dietetics SARS-CoV-2 business.industry COVID-19 Parenteral nutrition Oxygen Case-Control Studies Non-invasive ventilation Breathing Original Article Observational study medicine.symptom business Body mass index De-escalation |
Zdroj: | Clinical Nutrition Espen |
ISSN: | 2405-4577 |
Popis: | Background & aims SARS-CoV-2 infection includes a variety of gastrointestinal manifestations along with the usual viral symptoms of malaise and myalgias. The objective of this study was to determine if intravenous parenteral nutrition (PN) affected the risk of intubation in SARS-CoV-2 patients who were dependent on non-invasive ventilation. Methods Retrospective, multicenter case-control study which analyzed oxygen requirements for 1974 adults with SARS-CoV-2, who were admitted to the local public hospital system between March 1 and May 17, 2020. Relevant baseline biomarkers were studied over 5 days. The main outcome was an escalation or de-escalation of oxygen requirements relative to the exposure of PN. Results 111 patients received PN while on non-invasive ventilation. Patients who received PN had a significantly lower odds (p |
Databáze: | OpenAIRE |
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