Effect of parenteral nutrition in oxygen escalation/de-escalation in SARS-CoV-2 infected patients who are pre-intubation: A multicenter, observational study

Autor: Farbod Raiszadeh, Gary Brandeis, Robert T. Faillace, Kritika Subramanian, Nadia Solomon, Vidya Menon
Rok vydání: 2021
Předmět:
Zdroj: Clinical Nutrition Espen
ISSN: 2405-4577
Popis: Background & aims SARS-CoV-2 infection includes a variety of gastrointestinal manifestations along with the usual viral symptoms of malaise and myalgias. The objective of this study was to determine if intravenous parenteral nutrition (PN) affected the risk of intubation in SARS-CoV-2 patients who were dependent on non-invasive ventilation. Methods Retrospective, multicenter case-control study which analyzed oxygen requirements for 1974 adults with SARS-CoV-2, who were admitted to the local public hospital system between March 1 and May 17, 2020. Relevant baseline biomarkers were studied over 5 days. The main outcome was an escalation or de-escalation of oxygen requirements relative to the exposure of PN. Results 111 patients received PN while on non-invasive ventilation. Patients who received PN had a significantly lower odds (p
Databáze: OpenAIRE