Hearing loss in humans drinking tube well water with high levels of iron in arsenic–polluted area
| Autor: | Anwarul A. Akhand, Nazmul Ahsan, Nobutaka Ohgami, Xiang Li, Kyoko Ohgami, Ichiro Yajima, Masashi Kato, Tingchao He, Reina Negishi-Oshino, Yoko Kato, Huadong Xu |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male Epidemiology Water Wells lcsh:Medicine Pilot Projects 0302 clinical medicine lcsh:Science Bangladesh Multidisciplinary geography.geographical_feature_category medicine.diagnostic_test integumentary system Auditory system Audiometry Pure-Tone Female Pure tone audiometry medicine.symptom Adult Hearing loss Tube well Iron chemistry.chemical_element Article Arsenic 03 medical and health sciences Young Adult Environmental health medicine otorhinolaryngologic diseases Humans Hearing Loss geography Potential risk business.industry Drinking Water lcsh:R Water Pollution 030104 developmental biology Increased risk chemistry Nails ROC Curve lcsh:Q Audiometry business 030217 neurology & neurosurgery Water Pollutants Chemical Water well Hair |
| Zdroj: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019) |
| ISSN: | 2045-2322 |
| Popis: | Well water for drinking with increased levels of iron in arsenic-polluted areas has been reported worldwide. Oral exposure to arsenic has been shown to be associated with hearing loss, while there is no evidence for an association between excessive exposure to iron and hearing loss in humans. In this study, we determined iron and arsenic levels in biological samples and hearing levels by pure tone audiometry (PTA) in subjects in a control area and an arsenic-polluted area in Bangladesh. The iron level in well water in the arsenic-polluted area was significantly higher than that in piped supply water in the control area. Subjects in the polluted area (n = 109), who had higher iron and arsenic levels in hair and toenails than those in subjects in the control area (n = 36), had an increased risk of hearing loss at 8 kHz and 12 kHz after adjustments for age, gender, smoking and BMI. Significant associations of the exposure group with hearing loss at 8 kHz and 12 kHz remained after further adjustment for arsenic levels in toenails and hair. Thus, this pilot study showed that excessive exposure to iron via drinking water is a potential risk for hearing loss in humans. |
| Databáze: | OpenAIRE |
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