Studies on anti-inflammatory, antipyretic and analgesic properties of Caesalpinia bonducella F. seed oil in experimental animal models
| Autor: | Shruti Shukla, Savita Shukla, Vivek K. Bajpai, Archana Mehta, Pradeep S. Mehta, Suresh P. Vyas |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.drug_class Analgesic Saccharomyces cerevisiae Carrageenan Toxicology Anti-inflammatory Body Temperature chemistry.chemical_compound Reaction Time Animals Edema Plant Oils Medicine Antipyretic Caesalpinia Hot plate test Acetic Acid Pain Measurement Behavior Animal Traditional medicine biology Foot business.industry Anti-Inflammatory Agents Non-Steroidal Experimental Animal Models General Medicine Analgesics Non-Narcotic biology.organism_classification Hindlimb Rats chemistry Seeds Female Licking business Food Science medicine.drug |
| Zdroj: | Food and Chemical Toxicology. 48:61-64 |
| ISSN: | 0278-6915 |
| DOI: | 10.1016/j.fct.2009.09.015 |
| Popis: | Caesalpinia bonducella FLEMING (Caesalpiniaceae) plant is well known for its medicinal and therapeutic values in Indian Ayurveda. However, to be clinically useful, more scientific data are needed. Therefore, in the present study, we investigated the effects of C. bonducella seed oil on acute and chronic inflammation. To assess the anti-inflammatory, antipyretic and analgesic activities, varied concentrations of the seed oil of C. bonducella (100, 200 and 400mg/kg orally) were tested in carrageenan-induced rat paw oedema, brewer's yeast-induced pyrexia, acetic acid-induced writhing and hot plate reaction time in experimental rats. The paw volumes, pyrexia and writhes in experimental rats were reduced significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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