Factors associated with fatal outcome in childhood meningococcal disease
| Autor: | Gutteberg T, Trond Flægstad, Stokland T, Per Ivar Kaaresen |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Ecchymosis Meningitis Meningococcal Neisseria meningitidis Logistic regression Meningococcal disease Severity of Illness Index Risk Factors Nasopharynx Intensive care Hyperventilation medicine Humans Vascular Diseases Risk factor Child Purpura Cyanosis Leukopenia business.industry Infant General Medicine Prognosis medicine.disease Meningococcal Infections Survival Rate Logistic Models El Niño Child Preschool Multivariate Analysis Pediatrics Perinatology and Child Health Female Base excess Hypotension medicine.symptom business |
| Zdroj: | Acta Paediatrica. 84:1137-1142 |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/j.1651-2227.1995.tb13513.x |
| Popis: | The purpose of this study was to identify factors associated with a fatal outcome in children with meningococcal disease and to design a new clinical scoring system. We reviewed the charts of all 137 children with meningococcal disease admitted alive to the University Hospital, Tromso, during the years 1977-92. Twelve of the children died (8.7%). On admission the following clinical signs were significantly associated with poor outcome : peripheral vasoconstriction, cyanosis, extensive petechiae, hypotension, altered consciousness, hyperventilation and absence of neck rigidity. The laboratory parameters low pH, low base excess, thrombocytopenia, low Trombotest and leukopenia were also associated with later death. Multiple logistic regression was performed to examine the independent effect of each variable. Cyanosis, peripheral vasoconstriction and base excess |
| Databáze: | OpenAIRE |
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