Extraneural Sclerosing Perineurioma of the Buccal Mucosa: A Case Report and Clinicopathologic Review
| Autor: | Sadru Kabani, Gilbert Brodsky, Vikki Noonan, David J. Greene |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Collagen Type IV
Male Pathology medicine.medical_specialty Adolescent Vimentin Case Report Extraneural Buccal mucosa Nerve Sheath Neoplasms Pathology and Forensic Medicine Perineurioma medicine Biomarkers Tumor Humans Peripheral Nerve Sheath Mouth neoplasm Sclerosis biology Mucin-1 Mouth Mucosa Anatomy Treatment Outcome Oncology Otorhinolaryngology biology.protein Mouth Neoplasms Nerve sheath neoplasm Immunostaining |
| Popis: | The perineurioma is an infrequently encountered benign peripheral nerve sheath tumor composed of a clonal proliferation of perineurial cells. Rare cases of perineurioma have been reported in the oral cavity. An extraneural sclerosing perineurioma arising in the buccal mucosa of a 17-year-old male is presented. Histopathologically, the tumor is composed of a well circumscribed nodular proliferation of spindle cells arranged in a storiform growth pattern, in some areas subtly arranged around vascular channels. The tumor cells reveal positive immunostaining for epithelial membrane antigen (EMA), collagen type IV and vimentin, and negative immunostaining for S-100 protein, consistent with a perineurial origin. To the best of our knowledge, this case represents the first report of an extraneural sclerosing perineurioma involving the oral cavity. |
| Databáze: | OpenAIRE |
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