Detection of Sars-Cov-2 antigens in thyroid gland showing histopathological features of subacute thyroiditis

Autor:	Hrvoje Jakovac, Antun Ferenčić, Christophe Stemberger, Bojana Mohar Vitezić, Dražen Cuculić
Rok vydání:	2022
Předmět:	Sars-Cov-2 BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti viruses Endocrinology Diabetes and Metabolism COVID-19 spike protein thyroid gland subacute thyroiditis
Zdroj:	European Thyroid Journal Volume 11 Issue 2
ISSN:	2235-0802
Popis:	The clinical and laboratory findings of subacute thyroiditis have been repeatedly reported as being associated with acute Sars-Cov-2 infection and post-COVID-19 syndrome. The exact mechanisms and histopathological correlations underlying thyroid involvement remained unresolved, but current insights suggest either direct viral damage, systemic inflammatory reaction, or an autoimmune response as possible noxious effectors. Here we present findings of immunohistochemical/immunofluorescence detection of Sars-Cov-2 viral proteins (spike/S and nucleocapside proteins) in relation to histoarchitectonic changes of autoptic thyroid tissue obtained from patient who deceased from COVID-19.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ca8452dac298c14b49c10af82be063 https://doi.org/10.1530/etj-22-0005 Zobrazit plný text záznamu