Columnar-Cell Carcinoma: Another Variant of Poorly Differentiated Carcinoma of the Thyroid
| Autor: | Manuel Sobrinho-Simões, Jan Vincents Johannessen, Jahn M. Nesland |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Male
Oncology medicine.medical_specialty Pathology medicine.medical_treatment Columnar Cell Metastasis Thyroid carcinoma Carcinoembryonic antigen Internal medicine Carcinoma medicine Humans Thyroid Neoplasms biology business.industry Thyroid General Medicine Middle Aged medicine.disease medicine.anatomical_structure Calcitonin biology.protein Thyroglobulin business |
| Zdroj: | American Journal of Clinical Pathology. 89:264-267 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/89.2.264 |
| Popis: | An unusual case of poorly differentiated carcinoma of the thyroid is reported. The tumor occurred in a 60-year-old man, who died with widespread metastases 5.5 years after primary treatment. The unencapsulated tumor measured 8 X 5 X 9.5 cm and was composed of columnar cells. Two to three mitotic figures per 10 high-power fields were present. The cells were thyroglobulin positive and not stained for calcitonin and carcinoembryonic antigen (CEA). The light microscopic appearance was similar to that of a metastasis from a carcinoma of the bowel. The authors conclude that columnar cell carcinoma is a separate type of thyroid carcinoma that shares the clinical properties of both follicular and papillary carcinoma and carries a poor prognosis. However, for practical purposes, the authors think that the tumor should be included in the category of poorly differentiated thyroid carcinomas together with the so-called insular carcinomas, mucoepidermoid carcinomas, and mucinous carcinomas. |
| Databáze: | OpenAIRE |
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