Three-dimensional impedance map analysis of rabbit liver
| Autor: | William D. O'Brien, Sandhya Sarwate, Alexander Dapore, Alexander D. Pawlicki |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Materials science
Acoustics and Ultrasonics Bioacoustics Imaging Three-Dimensional Arts and Humanities (miscellaneous) medicine Image Processing Computer-Assisted Animals Scattering Radiation Ultrasonics Electrical impedance Ultrasonography Staining and Labeling Scattering Liver cell Fatty liver Rabbit (nuclear engineering) medicine.disease Jasa Express Letters Fatty Liver Disease Models Animal medicine.anatomical_structure Liver Rabbits Acoustic impedance Nucleus Biomedical engineering |
| Popis: | Three-dimensional impedance maps (3DZMs) are computational models of acoustic impedance of tissue constructed from histology images. 3DZMs can be analyzed to estimate model-based quantitative ultrasound parameters such as effective scatterer diameter (ESD). In this study, 3DZMs were constructed from normal and fatty rabbit livers. Estimates of ESD were made using the fluid-filled sphere scattering model. Weighting toward smaller scatterer sizes produced ESD estimates of 7.5 ± 1.3 and 7.0 ± 0.3 μm for normal and fatty liver, respectively, approximately the size of a liver cell nucleus. This suggests the nucleus could be a primary source of scattering in liver. |
| Databáze: | OpenAIRE |
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