Positional device therapy for the treatment of positional obstructive sleep apnea in children: a pilot study
| Autor: | Evan J. Propst, Adele Baker, Nikolaus E. Wolter, Lena Xiao, Giorge Voutsas, Indra Narang, Colin Massicotte |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Supine position Polysomnography medicine.medical_treatment Polysomnogram Pilot Projects Interquartile range Internal medicine mental disorders Supine Position medicine Humans Mass index Continuous positive airway pressure Child Sleep Apnea Obstructive Continuous Positive Airway Pressure business.industry General Medicine medicine.disease Obstructive sleep apnea Cardiology Observational study Median body business psychological phenomena and processes |
| Zdroj: | Sleep Medicine. 85:313-316 |
| ISSN: | 1389-9457 |
| DOI: | 10.1016/j.sleep.2021.07.036 |
| Popis: | Background There is a critical gap in identifying effective interventions for children with obstructive sleep apnea (OSA) who do not tolerate continuous positive airway pressure therapy. Positional OSA (POSA) is a common clinical phenotype whereby OSA occurs predominantly while sleeping in supine position. POSA may be amenable to treatment with a positional device, a belt worn around the chest with cushions on the back to prevent supine positioning, but no data exists in children. The primary aim of this study was to evaluate the efficacy of positional device therapy for the treatment of POSA in children. Methods This observational study included children aged 4–18 years with POSA and an obstructive apnea-hypopnea index (OAHI) ≥ 5 events/hour on baseline polysomnogram (PSG) who underwent a second PSG to evaluate the efficacy of a positional device. The primary outcome was the change in OAHI. Results Ten children were included (8 male, median age 11.2 years, median body mass index z-score 1.6). Compared to the baseline PSG, PSG data obtained while using a positional device showed a reduced median (interquartile range) OAHI (15.2 [8.3–25.6] versus 6.7 [1.0–13.7] events/hour respectively; p = 0.004) and percentage of total sleep time in supine position (54.4 [35.0–80.6]% versus 4.2 [1.1–25.2]% respectively; p = 0.04). Despite observed improvements in the oxygen desaturation index, these results were not statistically significant. Significance and conclusions In this novel pilot study, positional device therapy was effective for the treatment of POSA. Positional device therapy may potentially change clinical practice as a cost-efficient and non-invasive treatment option for POSA. |
| Databáze: | OpenAIRE |
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