Methicillin-resistant Staphylococcus aureus among urban rodents, house shrews, and patients in Guangzhou, Southern China
| Autor: | Shu-ting Huo, Xue-Jiao Chen, Yun Mo, Jing Ge, Xue-shan Zhong, Yi-Quan Xiong, Ming-ji Cheng, Qing Chen, Min Qiu |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Methicillin-Resistant Staphylococcus aureus
China Rodent Virulence Factors Rodentia Microbial Sensitivity Tests Staphylococcal infections medicine.disease_cause Antimicrobial resistance Microbiology Antibiotic resistance biology.animal Drug Resistance Bacterial medicine Animals Humans Cities Molecular Epidemiology lcsh:Veterinary medicine House shrew General Veterinary Molecular epidemiology biology Shrews Shrew General Medicine Suncus biochemical phenomena metabolism and nutrition Staphylococcal Infections medicine.disease biology.organism_classification bacterial infections and mycoses Methicillin-resistant Staphylococcus aureus Urban rodent lcsh:SF600-1100 Multilocus sequence typing Multilocus-sequence typing Research Article Multilocus Sequence Typing |
| Zdroj: | BMC Veterinary Research BMC Veterinary Research, Vol 15, Iss 1, Pp 1-8 (2019) |
| ISSN: | 1746-6148 |
| Popis: | Background The transmission of methicillin-resistant Staphylococcus aureus (MRSA) between humans and animals has been identified in a number of countries. In this study, MRSA in urban rodents and shrews in a community was investigated. Further, comparisons of MRSA isolates from rodents, shrews, and humans were conducted to evaluate the relationships of these isolates from different origins. Results Between 2015 and 2016, 397 oropharynx samples from 212 rodents and 185 shrews, and 8 MRSA isolates from hospital patients were collected. Twelve MRSA were isolated from the small mammals (3.0, 95%CI: 1.3–4.7%), including 11 isolates from rodents and one from a shrew. Three MRSA isolates from Rattus norvegicus were PVL-positive, and seven isolates were IEC-negative (one from Suncus murinus, five from Rattus norvegicus, and one from a patient). The spa type, MLST, and antimicrobial resistance patterns showed that the MRSA retrieved from rodents and shrews are likely related to human strains. Conclusion MRSA derived from rodent shares similar antimicrobial resistance and molecular characteristics to those from humans, suggesting that urban rodents may play as maintenance host or vectors for MRSA which is important to human health. |
| Databáze: | OpenAIRE |
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