The impact of charlson comorbidity index on mortality from SARS‐CoV‐2 virus infection and A novel COVID‐19 mortality index: CoLACD
| Autor: | Cagri Atasoy, Berna Komurcuoglu, Ali Kadri Cirak, Günseli Balcı, Yelda Varol, Sena Ataman, Berrin Akkol, Enver Yalniz, Eda Bayramic, Gülru Polat, Sinem Ermin, Burcin Hakoglu |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate statistics Coronavirus disease 2019 (COVID-19) Adolescent Youden's J statistic Comorbidity Sensitivity and Specificity Young Adult Risk Factors Internal medicine Risk of mortality Medicine Humans Hospital Mortality Respiratory Medicine Aged Retrospective Studies Original Paper business.industry SARS-CoV-2 Area under the curve COVID-19 General Medicine Odds ratio Middle Aged medicine.disease Prognosis Original Papers Pneumonia Charlson comorbidity index Female business |
| Zdroj: | International Journal of Clinical Practice |
| ISSN: | 1742-1241 1368-5031 |
| Popis: | Objective The aim of this study is to find out the potential risk factors including charlson comorbidity index (CCI) score associated with death in COVID‐19 patients hospitalised because of pneumonia and try to find a novel COVID‐19 mortality score for daily use. Methods All patients diagnosed as confirmed or probable COVID‐19 pneumonia whom hospitalised in our Chest Diseases Education and Research Hospital between March 11, 2020 and May 15, 2020 were enrolled. The optimal cut‐off values, sensitivity and specificity values and odds ratios to be used in mortality prediction of the novel scoring system created from these parameters were calculated by ROC analysis according to the area under the curve and Youden index. Results Over 383 patients (n: 33 deceased, n: 350 survivors) univariate and multivariate regression analysis showed that CCI and lymphocyte ratio were prognostic factors for COVID‐19‐related mortality. Using this analysis, a novel scoring model CoLACD (CoVID‐19 Lymphocyte ratio, Age, CCI score, Dyspnoea) was established. The cut‐off value of this scoring system, which determines the mortality risk in patients, was 2.5 points with 82% sensitivity and 73% specificity (AUC = 0.802, 95% CI 0.777‐0.886, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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