Camptocormia in Japanese patients with Parkinson's disease: A multicenter study

Autor: Morinobu, Seki, Kazushi, Takahashi, Atsuo, Koto, Ban, Mihara, Yoko, Morita, Kazuo, Isozumi, Kouichi, Ohta, Kazuhiro, Muramatsu, Jun, Gotoh, Keiji, Yamaguchi, Yutaka, Tomita, Hideki, Sato, Yoshihiro, Nihei, Satoko, Iwasawa, Norihiro, Suzuki
Rok vydání: 2011
Předmět:
Zdroj: Movement Disorders. 26:2567-2571
ISSN: 0885-3185
DOI: 10.1002/mds.23955
Popis: Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms. © 2011 Movement Disorder Society
Databáze: OpenAIRE