Camptocormia in Japanese patients with Parkinson's disease: A multicenter study
Autor: | Morinobu, Seki, Kazushi, Takahashi, Atsuo, Koto, Ban, Mihara, Yoko, Morita, Kazuo, Isozumi, Kouichi, Ohta, Kazuhiro, Muramatsu, Jun, Gotoh, Keiji, Yamaguchi, Yutaka, Tomita, Hideki, Sato, Yoshihiro, Nihei, Satoko, Iwasawa, Norihiro, Suzuki |
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Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty Constipation Parkinson's disease Cross-sectional study Urinary incontinence Comorbidity Severity of Illness Index Spinal Curvatures Antiparkinson Agents Levodopa Muscular Atrophy Spinal Camptocormia Asian People Japan Internal medicine Severity of illness Epidemiology Prevalence medicine Humans Aged Aged 80 and over business.industry Parkinson Disease medicine.disease Cross-Sectional Studies Neurology Physical therapy Female Neurology (clinical) medicine.symptom business |
Zdroj: | Movement Disorders. 26:2567-2571 |
ISSN: | 0885-3185 |
DOI: | 10.1002/mds.23955 |
Popis: | Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms. © 2011 Movement Disorder Society |
Databáze: | OpenAIRE |
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