Paracetamol preceding very preterm birth: Is it safe?

Autor:	Aliisa Laitala, Timo Saarela, Marja Vääräsmäki, Mikko Hallman, Outi Aikio
Rok vydání:	2022
Předmět:	pain therapy Infant Newborn blood pressure Obstetrics and Gynecology Infant Apgar scores General Medicine Infant Premature Diseases premature infant respiratory support Pregnancy Humans Premature Birth Female Prospective Studies Infant Premature acetaminophen Acetaminophen
Zdroj:	Acta obstetricia et gynecologica Scandinavica. 101(8)
ISSN:	1600-0412
Popis:	Introduction: The use of paracetamol for pain relief in pregnancy is common. However, the influence of paracetamol on the perinatal adaptation of high-risk infants has not been studied. These data are important for safety, since another inhibitor of prostaglandin synthesis is harmful to infants born very preterm and increases serious morbidity. We studied whether the use of paracetamol had an adverse influence on neonatal adaptation and the outcomes of infants during the first hospitalization. Material and Methods: We studied the patient records of high-risk mothers and their infants born before 32 weeks of gestation for multiple variables over a period of 84 months in Oulu University Hospital, a regional tertiary care hospital caring for high-risk deliveries and providing neonatal intensive care. In a matched cohort setting, the exposition was defined as paracetamol use
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a95a28c5c38a966b6b8b638e3c04d5 https://pubmed.ncbi.nlm.nih.gov/35706332 Zobrazit plný text záznamu Plný text