Spherical arena reveals optokinetic response tuning to stimulus location, size, and frequency across entire visual field of larval zebrafish
| Autor: | Rebecca Meier, Florian A. Dehmelt, Aristides B. Arrenberg, Kun Wang, Takeshi Yoshimatsu, Clara A Simacek, Tom Baden, Ruoyu Huang, Julian Hinz |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
visual field genetic structures QH301-705.5 Visual space Science Sensory system Mice Transgenic Stimulus (physiology) optokinetic response General Biochemistry Genetics and Molecular Biology Retina 03 medical and health sciences Mice retinal photoreceptors 0302 clinical medicine yoking Animals Humans Biology (General) stimulus tuning Zebrafish Nystagmus Optokinetic Physics General Immunology and Microbiology biology General Neuroscience General Medicine Optokinetic reflex biology.organism_classification Gaze eye diseases Visual field 030104 developmental biology Larva Medicine Female Spatial frequency Visual Fields Neuroscience 030217 neurology & neurosurgery Photic Stimulation asymmetry Research Article |
| Zdroj: | eLife, Vol 10 (2021) eLife |
| ISSN: | 2050-084X |
| Popis: | Many animals have large visual fields, and sensory circuits may sample those regions of visual space most relevant to behaviours such as gaze stabilisation and hunting. Despite this, relatively small displays are often used in vision neuroscience. To sample stimulus locations across most of the visual field, we built a spherical stimulus arena with 14,848 independently controllable LEDs. We measured the optokinetic response gain of immobilised zebrafish larvae to stimuli of different steradian size and visual field locations. We find that the two eyes are less yoked than previously thought and that spatial frequency tuning is similar across visual field positions. However, zebrafish react most strongly to lateral, nearly equatorial stimuli, consistent with previously reported spatial densities of red, green, and blue photoreceptors. Upside-down experiments suggest further extra-retinal processing. Our results demonstrate that motion vision circuits in zebrafish are anisotropic, and preferentially monitor areas with putative behavioural relevance. |
| Databáze: | OpenAIRE |
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