Immunochemical Studies on Shigella dysenteriae Lipopolysaccharides

Autor: Irina L. Hofman, Leon V. Backinowsky, Nikolay K. Kochetkov, Vjacheslav L. Lvov, Boris A. Dmitriev
Rok vydání: 1973
Předmět:
Zdroj: European Journal of Biochemistry. 40:355-359
ISSN: 1432-1033
0014-2956
DOI: 10.1111/j.1432-1033.1973.tb03204.x
Popis: An investigation of the sugar composition of lipopolysaccharides derived from ten well-defined Shigella dysenteriae serotypes and two Escherichia alcalescens-dispar serotypes was carried out. All the lipopolysaccharides contained glucosamine, glucose, galactose, heptose and 3-deoxyoctulosonic acid. These sugars were considered to represent the core polysaccharide and the same sugars except heptose and 3-deoxyoctulosonic acid, may represent the constituents of the O-specific polysaccharide chains. In addition to the “basal” sugars, the following monosaccharides were detected as components of the various Sh. dysenteriae lipopolysaccharides: galactosamine, mannose, fucose, rhamnose and 3,6-dideoxyhexose. As a result, a chemical classification of Sh. dysenteriae lipopolysaccharides into eight chemotypes was suggested. The sugar composition of lipopolysaccarides from serologically related Shigella and Escherichia species was compared and several cross-reacting pairs were found to belong to the same chemotype.
Databáze: OpenAIRE