The Response to Atropine Sulfate Given by Aerosol and Intramuscular Routes to Patients Undergoing Fiberoptic Bronchoscopy
| Autor: | Donald C. Zavala, Kenneth Godsey, George N. Bedell |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Atropine Male Pulmonary and Respiratory Medicine Premedication medicine.medical_treatment Bronchi Critical Care and Intensive Care Medicine Injections Intramuscular FEV1/FVC ratio Bronchoscopy Reflex Atropine sulfate Fiber Optic Technology Humans Medicine Saline Aerosolization Aged Aerosols Bronchial Spasm Inhalation business.industry Middle Aged respiratory system Asthma Anesthesia Female Lung Volume Measurements Cardiology and Cardiovascular Medicine business Intramuscular injection medicine.drug |
| Zdroj: | Chest. 79:512-515 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.79.5.512 |
| Popis: | Two groups of 11 patients each were studied in their responses to intramuscular (IM) or aerosolized atropine sulfate, given in preparation for fiberoptic bronchoscopy. The patients in group 1 received 1.0 mg of atropine IM, and those in group 2 were given a prepared solution of atropine in saline (5 mg/ml) at a dosage of 0.1 mg/kg by nebulization (IPPB). Statistical analysis of the FVC, FEV 1 , FEF 25–76% , and FEF max showed excellent protective bronchodilatory effects of both IM and aerosolized atropine. In fact, the beneficial result was more prolonged when the drug was administered by inhalation. One possible factor to consider, however, is that atropine given by the aerosol route did not inhibit the vasovagal response in three of the 11 patients. Another factor to take into account is that atropine by IM injection is quicker to administer, more convenient, and requires less instrumentation than atropine given by aerosol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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