Multicentric Giant Cell Tumor of the Fourth and Fifth Metacarpals with Lung Metastases

Autor: Justin Floyd, Steven L. Jones, Nash H. Naam, Esat I. Memisoglu
Rok vydání: 2013
Předmět:
Zdroj: HAND. 9:389-392
ISSN: 1558-9455
1558-9447
Popis: Giant cell tumors of bone (GCTB) are generally benign neoplasms, but recently, some authors consider them to be low-grade malignant neoplasms because they have a relatively high rate of recurrence and at least some potential for metastases. The majority of GCTB are unifocal, and less than 1 % are multicentric. We report a rare case of a multicentric GCTB arising simultaneously in the non-dominant fourth and fifth metacarpals of a 25-year-old female. The patient underwent ray amputation of the two involved digits, and the surgical margins were histologically negative for tumor. The tumor had the classic histologic appearance of a benign GCTB. A year after the amputation, the patient developed pulmonary metastasis which was treated with pulmonary lobe resection. She is currently over 2.5 years ***post-surgical treatment of the primary lesion with no evidence of local recurrence or distant metastasis.
Databáze: OpenAIRE
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