Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-up

Autor: Keith D. Lindor, Evangelos Kalaitzakis, Matthias Neuhauser, Roberta A. Jorgensen, Einar Björnsson, Jayant A. Talwalkar, Roger W. Chapman, Felicity Enders, Hardy Maetzel
Jazyk: angličtina
Rok vydání: 2016
Předmět:
DOI: 10.1111/j.1478-3231.2009.02160.x
Popis: Background: Fatigue was recently suggested to predict an increased risk of mortality in a primary biliary cirrhosis (PBC) cohort during follow-up. Aims: To analyse the impact of fatigue on prognosis in PBC. Methods: Patients with PBC who had earlier completed the fatigue impact scale (FIS) were identified. Prognosis in terms of death and liver transplantation (Tx) was determined. Results: FIS values at baseline were analysed from 208 patients (192 females; median age 59 years (interquartile range 51–67), median follow-up of 5 years. Overall, 181 patients were alive at follow-up, 22 (12%) died and five (2.4%) underwent transplantation. FIS at baseline was 28 (12–47) and FIS at follow-up was 25 (8–64) (P
Databáze: OpenAIRE