Fatigue measurements in patients with primary biliary cirrhosis and the risk of mortality during follow-up
Autor: | Keith D. Lindor, Evangelos Kalaitzakis, Matthias Neuhauser, Roberta A. Jorgensen, Einar Björnsson, Jayant A. Talwalkar, Roger W. Chapman, Felicity Enders, Hardy Maetzel |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Male
medicine.medical_specialty Minnesota medicine.medical_treatment Comorbidity Liver transplantation Gastroenterology Primary biliary cirrhosis Interquartile range Sickness Impact Profile Internal medicine medicine Risk of mortality Humans Survival rate Fatigue Aged Sweden Hepatology Liver Cirrhosis Biliary business.industry Hazard ratio Middle Aged Prognosis medicine.disease United Kingdom Liver Transplantation Surgery Survival Rate Transplantation Cohort Female business Follow-Up Studies |
DOI: | 10.1111/j.1478-3231.2009.02160.x |
Popis: | Background: Fatigue was recently suggested to predict an increased risk of mortality in a primary biliary cirrhosis (PBC) cohort during follow-up. Aims: To analyse the impact of fatigue on prognosis in PBC. Methods: Patients with PBC who had earlier completed the fatigue impact scale (FIS) were identified. Prognosis in terms of death and liver transplantation (Tx) was determined. Results: FIS values at baseline were analysed from 208 patients (192 females; median age 59 years (interquartile range 51–67), median follow-up of 5 years. Overall, 181 patients were alive at follow-up, 22 (12%) died and five (2.4%) underwent transplantation. FIS at baseline was 28 (12–47) and FIS at follow-up was 25 (8–64) (P |
Databáze: | OpenAIRE |
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