Treatment Duration of Febrile Urinary Tract Infections

Autor: Jaap T. van Dissel, Cees van Nieuwkoop, Willize E. van der Starre
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Current Infectious Disease Reports
ISSN: 1534-3146
1523-3847
Popis: Although febrile urinary tract infections (UTIs) are relatively common in adults, data on optimal treatment duration are limited. Randomized controlled trials specifically addressing the elderly and patients with comorbidities have not been performed. This review highlights current available evidence. Premenopausal, non-pregnant women without comorbidities can be treated with a 5–7 day regimen of fluoroquinolones in countries with low levels of fluoroquinolone resistance, or, if proven susceptible, with 14 days of trimethoprim-sulfamethoxazole. Oral β-lactams are less effective compared with fluoroquinolones and trimethoprim-sulfamethoxazole. In men with mild to moderate febrile UTI, a 2-week regimen of an oral fluoroquinolone is likely sufficient. Although data are limited, this possibly holds even in the elderly patients with comorbidities or bacteremia.
Databáze: OpenAIRE