Prevalence of ocular fundus pathology in patients with chronic kidney disease
| Autor: | Akinlolu O. Ojo, Juan E. Grunwald, John W. Kusek, Revell Whittock, Crystal A. Gadegbeku, James P. Lash, Maureen G. Maguire, Raymond R. Townsend, Jeffrey C. Fink, Harold I. Feldman, Joan C. Lo, Mahaboob Rahman, Judith Alexander, Candace Parker, Kathleen McWilliams |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Pathology medicine.medical_specialty genetic structures Epidemiology Cross-sectional study Fundus Oculi Population Fundus (eye) Diagnostic Techniques Ophthalmological Critical Care and Intensive Care Medicine urologic and male genital diseases Kidney Risk Assessment Retina Retinal Diseases Risk Factors Odds Ratio Prevalence Medicine Humans Longitudinal Studies Renal Insufficiency Chronic education Aged Transplantation education.field_of_study Chi-Square Distribution medicine.diagnostic_test business.industry Odds ratio Original Articles Middle Aged medicine.disease eye diseases United States Cross-Sectional Studies Logistic Models Nephrology Eye examination Cohort Female sense organs business Kidney disease Retinopathy Glomerular Filtration Rate |
| Zdroj: | Clinical journal of the American Society of Nephrology : CJASN. 5(5) |
| ISSN: | 1555-905X |
| Popis: | Background and objectives: The objective of this study was to describe the prevalence of ocular fundus pathology in the Chronic Renal Insufficiency Cohort (CRIC) study, a multicenter, longitudinal study of individuals with varying stages of chronic kidney disease (CKD). Design, setting, participants, & measurements: In this cross-sectional study, 45° digital photos of the disc and macula in both eyes were obtained by nonophthalmologic personnel using a nonmydriatic Canon CR-DGI fundus camera in 1936 individuals who participated in the CRIC study. Photographs were assessed in a masked manner by graders and a retinal specialist at a central photograph reading center. The purpose of this review was to inform participants quickly of conditions that warranted a complete eye examination by an ophthalmologist. Results: Among the 1936 participants who were photographed, 1904 (98%) had assessable photographs in at least one eye. Eye pathologies that required a follow-up examination by an ophthalmologist were identified in 864 (45%) of these 1904 participants. These eye pathologies included, among others, retinopathy (diabetic and/or hypertensive), a finding that was observed in 482 (25%) of these 1904 participants. Three percent (65 participants) of the 1904 participants had serious eye conditions that required urgent follow-up and treatment. Lower estimated GFR and cardiovascular disease were associated with greater eye pathology. Estimated GFR |
| Databáze: | OpenAIRE |
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