Optical biosensing for label-free cellular studies

Autor: Hans J. Griesser, Benjamin Thierry, Régis Méjard
Přispěvatelé: Mejard, Regis, Griesser, Hans J, Thierry, Benjamin
Rok vydání: 2014
Předmět:
Zdroj: TrAC Trends in Analytical Chemistry. 53:178-186
ISSN: 0165-9936
Popis: Optical biosensors such as waveguides and surface-plasmon resonance (SPR) sensors have found numerous applications in biomolecular sciences. We provide an overview of these technologies in relation to the specific requirements of label-free and high-throughput cellular studies. We dedicate specific emphasis to SPR-based biosensors and recent developments particularly suitable for cellular studies, such as long-range SPR. We discuss the advantages and the disadvantages of the most successful optical-sensing technologies, and potential approaches in the next generation of optical technologies. Refereed/Peer-reviewed
Databáze: OpenAIRE