Obstructive Sleep Apnea in Apertʼs and Pfeifferʼs Syndromes
| Autor: | William H. Perloff, Roger C. Mixter, David J. David, Christopher G. Green, Peter M. Popic, Richard M. Pauli |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male musculoskeletal diseases congenital hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Adolescent Craniofacial abnormality Apert syndrome Sleep Apnea Syndromes Bronchoscopy medicine Humans Child business.industry Skull Respiratory disease Infant Newborn Infant Apnea Acrocephalosyndactylia Middle Aged medicine.disease Trachea Obstructive sleep apnea El Niño Child Preschool Face Anesthesia Pfeiffer syndrome Female Surgery medicine.symptom Complication business |
| Zdroj: | Plastic and Reconstructive Surgery. 86:457-463 |
| ISSN: | 0032-1052 |
| DOI: | 10.1097/00006534-199009000-00011 |
| Popis: | Nine acrocephalosyndactyly type I patients (Apert's syndrome) and three acrocephalosyndactyly type V patients (Pfeiffer's syndrome) were evaluated for the relative importance of upper and lower airway abnormalities in the generation of obstructive sleep apnea. All patients were found to have a combination of upper and lower abnormalities. The influence of lower pathology was greater in the infants, and the influence of upper airway, specifically pharyngeal, was greater in the adults. A comparison between preoperative and postoperative polysomnography revealed little improvement with standard craniofacial advancements. Furthermore, three patients are described who succumbed to pulmonary death despite tracheostomy. Conservative treatment with prone or lateral positioning and medical pulmonary regimens is advocated. Finally, the pathogenesis of this diffuse airway pathology is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|