Current Management of Bleeding Peptic Ulcer
| Autor: | Robert P. Walt, Marios Z. Panos |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
medicine.medical_specialty
Resuscitation Population Endoscopy Gastrointestinal Pharmacotherapy Recurrence Electrocoagulation medicine Humans Pharmacology (medical) Stomach Ulcer Risk factor education Misoprostol Omeprazole Monitoring Physiologic education.field_of_study business.industry Incidence (epidemiology) Middle Aged Anti-Ulcer Agents Surgery Peptic Ulcer Hemorrhage Duodenal Ulcer Emergency medicine business Tranexamic acid medicine.drug |
| Zdroj: | Drugs. 46:269-280 |
| ISSN: | 0012-6667 |
| DOI: | 10.2165/00003495-199346020-00005 |
| Popis: | In the United Kingdom, acute bleeding from peptic ulcer is estimated to account for 25 admissions to hospital per 100 000 population annually. Overall mortality has been reported at around 10%. Accurate initial assessment for the identification of high risk groups, prompt resuscitation, close monitoring and timely intervention for rebleeding improves survival. In patients not responding to initial resuscitation and those who rebleed, emergency endoscopy identifies the source of bleeding in the majority and is essential to enable endoscopic therapy. Injection of a vasoconstrictor and/or sclerosant into a visible or bleeding vessel, or thermal coagulation, reduces the incidence of rebleeding and probably decreases mortality. In general terms, ‘early’ surgical intervention is indicated for those aged over 60 years in whom bleeding recurs or continues despite endoscopic measures. The low mortality ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink