The influence of chronic preoperative propranolol therapy on cardiovascular dynamics and narcotic requirements during operation in patients with coronary artery disease
| Autor: | Theodore H. Stanley, Simon de Lange, Norbert de Bruijn, M. J. Boscoe |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Narcotics
Nitroprusside medicine.medical_specialty Sufentanil Narcotic medicine.medical_treatment Nitrous Oxide Coronary Disease Propranolol Anesthesia General Coronary artery disease Internal medicine Anesthesiology medicine Humans Coronary Artery Bypass Phentolamine business.industry Unconsciousness Hemodynamics General Medicine Middle Aged medicine.disease Fentanyl Anesthesiology and Pain Medicine medicine.anatomical_structure Blood pressure Anesthesia Cardiology medicine.symptom business Artery medicine.drug |
| Zdroj: | Canadian Anaesthetists’ Society Journal. 29:319-324 |
| ISSN: | 1496-8975 0008-2856 |
| DOI: | 10.1007/bf03007519 |
| Popis: | We measured the dose of sufentanil required for unconsciousness as well as the entire operation in 44 patients (22 taking propranolol and 22 not taking propranolol) undergoing coronary artery bypass grafting (CABG) operations. The incidence of hypertension during operation, requirements for supplements to treat hypertension and recovery times were also determined. The data indicate that patients undergoing CABG operations taking propranolol require significantly less sufentanil for unconsciousness and the entire operation than patients not taking this drug. In spite of requiring less sufentanil, patients taking propranolol had less hypertension during operation and thus required less supplements. However recovery times in both groups were the same. The results of this study may partially explain the varying incidence of hypertension reported during high dose fentanyl and other narcotic-oxygen anaesthetic techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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