Synthesis and -characterization of new N-substituted 2-aminopyrrole derivatives

Autor: Ferhan Tümer, Kadir Aksu, Bünyamin Özgeriş
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Organic Communications, Vol 12, Pp 38-42 (2019)
ISSN: 1307-6175
Popis: In this work, new N-substituted 2-aminopyrrole derivatives were synthesized. Initially, some crotonitriles were prepared by condensation of malononitrile with arylmethylketones, which was followed by conversion of them to the bromocrotonitriles. Finally, the synthesis of new N-substituted 2-aminopyrrole derivates were successfully achieved by cyclization of the bromocrotonitriles of (R)-1-phenylethylamine applying Gewald method.  
Databáze: OpenAIRE