Morphometric investigations on the portal tracts of the liver, the differentiation of variable progression in chronic persistent hepatitis
Autor: | C. J. Lüders, J. Volmer |
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Rok vydání: | 1981 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Histology Biopsy Virus Hepatitis Pathology and Forensic Medicine Liver tissue medicine Humans Molecular Biology Pathological Hepatitis B Surface Antigens Variable progression business.industry Significant difference Chronic persistent hepatitis Cell Biology General Medicine Portal tracts Middle Aged Prognosis medicine.disease Liver Chronic Disease Female Anatomy business |
Zdroj: | Virchows Archiv A Pathological Anatomy and Histology. 392:321-337 |
ISSN: | 1432-2307 0340-1227 |
DOI: | 10.1007/bf02155669 |
Popis: | Morphometric investigations were carried out on the portal tracts of the liver in different forms of chronic hepatitis. The investigation groups each contained 25 liver biopsies, which were subdivided into cases with normal liver, a subsiding acute virus hepatitis, three different forms of chronic persistent hepatitis (CPH) and chronic aggressive hapatitis type IIa (CAH IIa). Determinations of the volume and surface of the portal tracts and their components enabled three forms of CPH (type Ia, Ib, Ic) to be characterised. Preliminary clinical and semiquantitative histological investigations were correlated with a significant difference in the histological characteristics and prognosis. HBsAg-positive and HBsAg-negative cases showed no significant morphologically detectable differences in all groups investigated. Morphometry is suitable for investigation of pathological changes in liver tissue, especially the portal tracts. |
Databáze: | OpenAIRE |
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